3D Modelling and Haemodynamic Analysis of Patient Specific Abdominal Aortic Aneurysms

In an age of increased demand for cardiovascular interventions – surgical but also minimally invasive – there is an urgent need for improved and reliable prognostics in patients presenting with abdominal aortic aneurysms. Is it possible to inform predictions of rupture risk using biomedical imaging data direct from the clinic? This work builds on pre-existing simplified computational models that couple the fluid dynamics of blood with the structural dynamics of aortic tissue.

Disciplines and Techniques

Project supervisor/s

Professor Richard Bomphrey

Richard's research sits at the interface of biology and engineering. I use biomechanics as a tool to investigate evolutionary biology and, specifically, how the physical environment determines the morphology and control systems of flying animals.

Royal Veterinary College

Yiannis Ventikos

Yiannis's research focuses on transport phenomena and fluid mechanics, as they are applied to biomedical engineering problems, energy, innovative industrial processes and biocomplexity

University College London

References

Fluid-structure interaction of turbulent pulsatile flow within a flexible wall axisymmetric aortic aneurysm model

Khanafer, K. M., Bull, J. L. and Berguer, R.

European Journal of Mechanics, B/Fluids. Elsevier Masson SAS, 28(1), pp. 88–102. doi: 10.1016/j.euromechflu.2007.12.003

2009

Fluid-structure interaction in abdominal aortic aneurysms: Effects of asymmetry and wall thickness

Scotti, C. M. et al.

BioMedical Engineering Online. doi: 10.1186/1475-925X-4-64

2005

Hemodynamic changes occurring during the progressive enlargement of abdominal aortic aneurysms

Salsac, A.-V., Sparks, S. R. and Lasheras, J. C

Annals of vascular surgery. doi: 10.1007/s10016-003-0101-3

2004

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3D Modelling and Haemodynamic Analysis of Patient Specific Abdominal Aortic Aneurysms