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3D Modelling and Haemodynamic Analysis of Patient Specific Abdominal Aortic Aneurysms

3d Modelling and haemodynamic Analysis

In an age of increased demand for cardiovascular interventions – surgical but also minimally invasive – there is an urgent need for improved and reliable prognostics in patients presenting with abdominal aortic aneurysms. Is it possible to inform predictions of rupture risk using biomedical imaging data direct from the clinic? This work builds on pre-existing simplified computational models that couple the fluid dynamics of blood with the structural dynamics of aortic tissue.

Disciplines and Techniques
Project supervisor/s
Professor Richard Bomphrey
Richard's research sits at the interface of biology and engineering. I use biomechanics as a tool to investigate evolutionary biology and, specifically, how the physical environment determines the morphology and control systems of flying animals.
Royal Veterinary College
Yiannis Ventikos
Yiannis's research focuses on transport phenomena and fluid mechanics, as they are applied to biomedical engineering problems, energy, innovative industrial processes and biocomplexity
University College London
Fluid-structure interaction of turbulent pulsatile flow within a flexible wall axisymmetric aortic aneurysm model
Khanafer, K. M., Bull, J. L. and Berguer, R.
European Journal of Mechanics, B/Fluids. Elsevier Masson SAS, 28(1), pp. 88–102. doi: 10.1016/j.euromechflu.2007.12.003
Fluid-structure interaction in abdominal aortic aneurysms: Effects of asymmetry and wall thickness
Scotti, C. M. et al.
BioMedical Engineering Online. doi: 10.1186/1475-925X-4-64
Hemodynamic changes occurring during the progressive enlargement of abdominal aortic aneurysms
Salsac, A.-V., Sparks, S. R. and Lasheras, J. C
Annals of vascular surgery. doi: 10.1007/s10016-003-0101-3